Original article
Published: 2025-10-24

EVALUATION OF THE PAN-IMMUNE-INFLAMMATION VALUE IN PATIENTS WITH BELL'S PALSY

Suleyman Demirel University
Yüksekova State Hospital
Süleyman Demirel University, Faculty of Medicine
Süleyman Demirel University, Faculty of Medicine
Bell palsy facial paralysis biomarkers neutrophils

Abstract

Objectives: Pan-immune-inflammation value is an inflammation index calculated using the parameters in a CBC and has gained popularity in recent years. In this study, we aimed to examine its role in Bell's palsy.

Methods:  The study was designed as a retrospective case-control study. The study group consisted of 79 Bell palsy patients. There were 158 patients in the control group. The age, gender, grade, CBC parameters and pan-immune-inflammation value were compared statistically between the groups.

Results: Leukocyte, neutrophil, platelet and pan-immune-inflammation values were significantly higher in Bell palsy group than in the control group (p values: <0.001, <0.001, 0.03, <0.001, respectively). There was no correlation between the Bell's palsy grade and any study parameters.

Conclusions: Our results support the theory that inflammation may be the main factor in pathogenesis, as the pan-immune-inflammation value is higher in patients with Bell's palsy. Our results suggest that the cell group that plays a major role in this inflammation is neutrophils.

Affiliations

Mehmet Emre Sivrice

Suleyman Demirel University

Vural Akın

Yüksekova State Hospital

Hasan Yasan

Süleyman Demirel University, Faculty of Medicine

Erdoğan Okur

Süleyman Demirel University, Faculty of Medicine

Copyright

© Società Italiana di Otorinolaringoiatria e chirurgia cervico facciale , 2025

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