Original article
Published: 2025-01-16

Clinicopathological and microbiological study of endoscopic surgery operated fungal rhinosinusitis

Otorhinolaryngology Clinic, University Medical Center “Zvezdara”, Belgrade, Serbia and Faculty of Dental Medicine, University of Belgrade, Belgrade, Serbia
Clinic for Otorhinolaryngology and Maxillofacial Surgery, Clinical Centre of Serbia, Belgrade, Serbia and Department of Otorhinolaryngology and Maxillofacial Surgery, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Clinic for Otorhinolaryngology and Maxillofacial Surgery, Clinical Centre of Serbia, Belgrade, Serbia and Department of Otorhinolaryngology and Maxillofacial Surgery, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Otorhinolaryngology Clinic, University Medical Center “Zvezdara”, Belgrade, Serbia
Otorhinolaryngology Clinic, University Medical Center “Zvezdara”, Belgrade, Serbia and Faculty of Special Education and Rehabilitation, University of Belgrade, Belgrade, Serbia
Institute of Pathology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Otorhinolaryngology Clinic, University Medical Center “Zvezdara”, Belgrade, Serbia

Abstract

Objective Rhinosinusitis is common disorder with great personal and economic impact. It is estimated that chronic rhinosinusitis affect 10-20% of the population.

Methods The descriptive study was done from January 2018 to December 2020 in two separate facilities: Otorhinolaryngology and Maxillofacial Surgery Clinic, University Clinical Centre of Serbia and Otorhinolaryngology Clinic, Clinical Hospital Centre “Zvezdara”, Belgrade, Serbia and included hospitalized patients with specific sinosanal symptoms. The data were obtained by processing medical charts of the patients.

Results The study included 11 patients who were hospitalized on the two Otorhinolaryngology Clinic in a two-year period. There were 6 (54,5%) female and 5 (44,5%) male patients. Most common symptoms were nasal obstructions, followed by hypersecretion, hyposmia and anosmia, respectively. The most common form of disease was allergic fungal rhinosinusitis in 6 cases (63,7%), followed by saprophytic fungal infestation and fungus ball, respectively.

Conclusions The most common forms of fungal rhinosinusitis are caused by: Scedosporium apiospermum, Penicillium spp. and Cladosporium spp. With the diagnosis of the correct type of fungus, adequate treatment could be adjust, and thus relapses could be more easily prevent.

Affiliations

Vladan Milutinović

Otorhinolaryngology Clinic, University Medical Center “Zvezdara”, Belgrade, Serbia and Faculty of Dental Medicine, University of Belgrade, Belgrade, Serbia

Aleksandar Trivić

Clinic for Otorhinolaryngology and Maxillofacial Surgery, Clinical Centre of Serbia, Belgrade, Serbia and Department of Otorhinolaryngology and Maxillofacial Surgery, Faculty of Medicine, University of Belgrade, Belgrade, Serbia

Ivana Ćolović-Čalovski

Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia

Jovica Milovanović

Clinic for Otorhinolaryngology and Maxillofacial Surgery, Clinical Centre of Serbia, Belgrade, Serbia and Department of Otorhinolaryngology and Maxillofacial Surgery, Faculty of Medicine, University of Belgrade, Belgrade, Serbia

Sanja Colić

Otorhinolaryngology Clinic, University Medical Center “Zvezdara”, Belgrade, Serbia

Snežana Babac

Otorhinolaryngology Clinic, University Medical Center “Zvezdara”, Belgrade, Serbia and Faculty of Special Education and Rehabilitation, University of Belgrade, Belgrade, Serbia

Nada Tomanović

Institute of Pathology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia

Zorana Radin

Otorhinolaryngology Clinic, University Medical Center “Zvezdara”, Belgrade, Serbia

Copyright

© Società Italiana di Otorinolaringoiatria e chirurgia cervico facciale , 2025

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